Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940832 | 0.76 | GABRA1 (0.36) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL8136318 | 0.65 | GABRA1 (0.57) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL8132569 | 0.64 | GABRA1 (0.55) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL2817756 | 0.64 | GABRA1 (0.55) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL7206360 | 0.63 | FABP3 (0.51) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL6941985 | 0.62 | SOAT2 (0.34) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7206345 | 0.62 | GABRA1 (0.41) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL2723046 | 0.61 | GABRA1 (0.61) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL7206347 | 0.61 | GABRA1 (0.43) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL28302057 | 0.60 | GABRA1 (0.65) | GABRA1GABRG2GABRB3SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |