Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206924 | 0.88 | SOAT2 (0.39) | GABRA1GABRB2SOAT2MYCSOAT1 | |
| SCHEMBL7212856 | 0.86 | AKR1B1 (0.41) | LMNACYP3A4HPGDHTR2CHTR2B | |
| SCHEMBL7206954 | 0.81 | SRD5A2 (0.34) | GABRA1GABRG2GABRB3TSHR | |
| SCHEMBL7206388 | 0.81 | TSHR (0.41) | SMN1; SMN2LMNAHPGDTSHRHIF1A | |
| SCHEMBL7206905 | 0.81 | NPC1 (0.30) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7207810 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNACYP3A4HPGDKMT2A | |
| SCHEMBL7206347 | 0.77 | GABRA1 (0.43) | GABRA1GABRG2GABRB3LPAR1SMN1; SMN2 | |
| SCHEMBL7212819 | 0.75 | TTR (0.53) | SMN1; SMN2LMNAHPGDTSHRHIF1A | |
| SCHEMBL7109320 | 0.75 | FABP3 (0.35) | SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7206377 | 0.74 | LMNA (0.37) | SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |