Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207662 | 0.90 | FABP4 (0.58) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL6940834 | 0.83 | FABP3 (0.44) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL27898710 | 0.75 | FABP3 (0.62) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL2380508 | 0.74 | FABP4 (0.60) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7207657 | 0.74 | FABP3 (0.44) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL8136318 | 0.73 | GABRA1 (0.57) | SOAT2MYCSOAT1MAP2K3GABRA1 | |
| SCHEMBL4327412 | 0.73 | FABP3 (0.58) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7206347 | 0.72 | GABRA1 (0.43) | SOAT2MYCSOAT1MAP2K3GABRA1 | |
| SCHEMBL5456119 | 0.72 | SOAT2 (0.67) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL2817756 | 0.72 | GABRA1 (0.55) | SOAT2MYCSOAT1MAP2K3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |