Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206928 | 0.85 | FABP3 (0.41) | GABRA1SOAT2MYCSOAT1MAP2K3 | |
| SCHEMBL7212859 | 0.84 | AKR1B1 (0.45) | LMNAKMT2ASMN1; SMN2CYP3A4HPGD | |
| SCHEMBL7206357 | 0.80 | GABRA1 (0.39) | GABRA1GABRG2GABRB3LPAR1SOAT2 | |
| SCHEMBL7206959 | 0.78 | GLRA1 (0.39) | SOAT2MYCSOAT1MAP2K3SCN5A | |
| SCHEMBL7206391 | 0.78 | MAPT (0.47) | LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL7206911 | 0.77 | HPGD (0.32) | HPGD | |
| SCHEMBL7206345 | 0.77 | GABRA1 (0.41) | GABRA1GABRG2GABRB3LPAR1SOAT2 | |
| SCHEMBL7207814 | 0.72 | NPC1 (0.39) | LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL7206360 | 0.72 | FABP3 (0.51) | GABRA1GABRG2GABRB3LPAR1SOAT2 | |
| SCHEMBL7212823 | 0.71 | L3MBTL1 (0.50) | KMT2ACYP1A2CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |