Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034647 | 0.81 | ALDH1A1 (0.52) | ALOX15KDM4EMAPK1ALDH1A1HIF1A | |
| SCHEMBL21034788 | 0.78 | ALOX15 (0.57) | ALOX15KDM4EMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL21034795 | 0.78 | ALOX15 (0.52) | ALOX15KDM4EMAPK1ALDH1A1HIF1A | |
| SCHEMBL5167973 | 0.76 | CNR1 (0.55) | ALOX15KDM4EMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL21002247 | 0.76 | ALOX15 (0.55) | ALOX15KDM4EALDH1A1CYP1A2MAPT | |
| SCHEMBL6948293 | 0.75 | GRIA4 (0.45) | LMNATP53RECQLTSHRKCNH2 | |
| SCHEMBL6940712 | 0.75 | GRIA4 (0.45) | LMNATP53RECQLTSHRKCNH2 | |
| SCHEMBL5165556 | 0.75 | GABRA1 (0.55) | RENALOX15KDM4EMAPK1ALDH1A1 | |
| SCHEMBL6949100 | 0.74 | ALOX5AP (0.48) | RENKDM4ECYP3A4CYP1A2CYP2D6 | |
| SCHEMBL6940748 | 0.74 | ALOX5AP (0.48) | RENKDM4ECYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |