Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943983 | 0.89 | DPP8 (0.49) | DPP8DPP9PREPRECQLKMT2A | |
| SCHEMBL6941021 | 0.88 | DPP8 (0.44) | DPP8DPP9PREPRECQLKMT2A | |
| SCHEMBL6943475 | 0.87 | DPP8 (0.44) | DPP8DPP9PREPRECQLKMT2A | |
| SCHEMBL6940996 | 0.86 | HDAC1 (0.38) | DPP8DPP9RECQLKMT2ATGM2 | |
| SCHEMBL6940993 | 0.86 | HDAC1 (0.38) | DPP8DPP9RECQLKMT2ATGM2 | |
| SCHEMBL6946787 | 0.85 | DPP8 (0.42) | DPP8DPP9PREPRECQLKMT2A | |
| SCHEMBL6945227 | 0.85 | DPP8 (0.51) | DPP8DPP9PREPALDH1A1TGM2 | |
| SCHEMBL9728223 | 0.82 | DPP8 (0.46) | DPP8DPP9 | |
| SCHEMBL9040433 | 0.81 | ALDH1A1 (0.41) | KMT2AALDH1A1GAAMAPTATM | |
| SCHEMBL9040592 | 0.81 | ALDH1A1 (0.41) | KMT2AALDH1A1GAAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |