SCHEMBL6941834

SCHEMBL6941834

CC(=O)Oc1ccc(CCC2=CC(=O)NC2=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
PTGS2 P35354 1/20 0.39
MAPT P10636 3/20 0.38
POLB P06746 2/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 2/20 0.38
TTR P02766 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ELANE P08246 1/20 0.37
GLA P06280 2/20 0.37
THRB P10828 1/20 0.37
GAA P10253 2/20 0.37
HSD17B10 Q99714 1/20 0.36
CACNA1B Q00975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9081470 0.79 LMNA (0.61) LMNASMN1; SMN2NPC1RAB9APTGS2
SCHEMBL30132966 0.73 MAOA (0.32)
SCHEMBL3825008 0.73 PARK7 (0.47) KMT2AMEN1HSD17B10
SCHEMBL717987 0.73 NPC1 (0.65) LMNASMN1; SMN2NPC1RAB9APTGS2
SCHEMBL718523 0.73 MAPT (0.56) LMNASMN1; SMN2NPC1RAB9APTGS2
SCHEMBL5422952 0.73 HSD17B10 (0.47) LMNASMN1; SMN2RAB9APTGS2MAPT
SCHEMBL23894744 0.72 LMNA (0.57) LMNASMN1; SMN2NPC1RAB9APTGS2
SCHEMBL1398019 0.72 GSK3A (0.32)
SCHEMBL17662334 0.72 LMNA (0.52) LMNASMN1; SMN2NPC1RAB9APTGS2
SCHEMBL2387797 0.72 LMNA (0.52) LMNASMN1; SMN2NPC1RAB9APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569972-B1 Photo-alignment materials for liquid crystal alignment film SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-05-27 US disclosed
EP-1281746-A2 Photo-alignment materials for liquid crystal alignment film SAMSUNG ELECTRONICS CO., LTD. (KR) 2003-02-05 EP disclosed