Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936615 | 0.78 | PPARG (0.36) | PTPN1PTPN11LMNAMAPTXBP1 | |
| SCHEMBL11684526 | 0.74 | HPGD (0.37) | PTPN1PTPN11ALOX5HPGDNPC1 | |
| SCHEMBL9080680 | 0.73 | L3MBTL1 (0.46) | PTPN1PTPN11LMNAL3MBTL1ALOX5 | |
| SCHEMBL18242591 | 0.72 | PTPN1 (0.41) | PTPN1PTPN11PRKCICA12MTNR1A | |
| SCHEMBL18243922 | 0.72 | PTPN1 (0.34) | PTPN1PTPN11GPR84PLK1MTNR1A | |
| SCHEMBL3633717 | 0.72 | FLT1 (0.34) | PTPN1PTPN11LMNAMAPTXBP1 | |
| SCHEMBL18242177 | 0.71 | ALOX5 (0.36) | PTPN1PTPN11MTNR1AALOX5HPGD | |
| SCHEMBL4960554 | 0.69 | HTT (0.53) | PTPN1PTPN11HIF1AALOX5HPGD | |
| SCHEMBL20681219 | 0.69 | MAPT (0.44) | PTPN1PTPN11LMNAMAPTXBP1 | |
| SCHEMBL5251259 | 0.69 | ALOX5 (0.33) | PTPN1PTPN11ALOX5HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003513909-A | — | — | 2003-04-15 | — | — | JP | claimed |
| EP-1229907-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001034127-A1 | PREVENTION OF PLAQUE RUPTURE BY ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-05-17 | — | — | WO | claimed |