SCHEMBL6942183

SCHEMBL6942183

CC(C)(C)c1cc(C2=Cc3cc([Si](C)(C)C)c([Si](C)(C)C)cc3C2)cc(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6940199 0.80 RXRB (0.33) KDM4EGAAMAPT
SCHEMBL6942040 0.79 CYP11B1 (0.36) S1PR1S1PR3KDM4EGAAMAPT
SCHEMBL6940536 0.76 CYP11B1 (0.37) KDM4EGAAMAPT
SCHEMBL6940332 0.76 CYP11B1 (0.35) S1PR1S1PR3KDM4EGAAMAPT
SCHEMBL6938203 0.74 RXRA (0.33)
SCHEMBL29897870 0.73 CYP11B1 (0.47)
SCHEMBL6280690 0.73 CYP11B1 (0.47)
SCHEMBL6939426 0.71 RXRB (0.39)
SCHEMBL28015474 0.66 TSHR (0.35) KDM4EMAPT
SCHEMBL6944595 0.64 S1PR1 (0.31) S1PR1S1PR3KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US claimed
EP-1157047-B1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORP NORTH AMERICA INC (US) 2003-04-23 EP disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed