Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | MMP13 | P45452 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP8 | P22894 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931077 | 0.73 | ADAM17 (0.34) | ADAM17HTR2ACTSCGAASMN1; SMN2 | |
| SCHEMBL6942867 | 0.72 | ADAM17 (0.68) | ADAM17MMP1MMP9MMP13MMP2 | |
| SCHEMBL7937182 | 0.72 | ADAM17 (0.36) | ADAM17MMP1MMP9MMP13CTSC | |
| SCHEMBL6942733 | 0.70 | ADAM17 (0.36) | ADAM17MMP1MMP9MMP13MMP2 | |
| SCHEMBL6940930 | 0.70 | ADAM17 (0.40) | ADAM17MMP1MMP9MMP13CTSC | |
| Hydrochloric Acid SCHEMBL7931109 | 0.69 | ADAM17 (0.31) | ADAM17 | |
| SCHEMBL7921611 | 0.67 | ADAM17 (0.35) | ADAM17MMP1MMP9MMP13HTR2A | |
| SCHEMBL7930087 | 0.66 | CTSC (0.37) | MMP1HTR2APSMB5CTSCMMP2 | |
| SCHEMBL7930090 | 0.66 | CTSC (0.37) | MMP1HTR2APSMB5CTSCMMP2 | |
| SCHEMBL7930092 | 0.66 | CTSC (0.37) | MMP1HTR2APSMB5CTSCMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |