Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939196 | 0.90 | PREP (0.44) | DPP8DPP9PREPSMN1; SMN2P2RX7 | |
| SCHEMBL6949361 | 0.90 | DPP8 (0.39) | DPP8DPP9PREPP2RX7RECQL | |
| SCHEMBL6944285 | 0.87 | DPP8 (0.45) | DPP8DPP9PREPP2RX7PKM | |
| SCHEMBL6943475 | 0.85 | DPP8 (0.44) | DPP8DPP9PREPLMNASMN1; SMN2 | |
| SCHEMBL6944029 | 0.84 | ATM (0.40) | ATM | |
| SCHEMBL6944292 | 0.84 | CCR5 (0.38) | NPC1RAB9ARECQLATM | |
| Dimethylamine SCHEMBL6944296 | 0.83 | ATM (0.38) | P2RX7ATM | |
| SCHEMBL6945390 | 0.82 | ALDH1A1 (0.37) | DPP8DPP9SMN1; SMN2P2RX7RECQL | |
| SCHEMBL6945782 | 0.81 | MMP9 (0.42) | SMN1; SMN2KMT2A | |
| SCHEMBL8988351 | 0.81 | DPP8 (0.39) | DPP8DPP9NPC1RAB9AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |