Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943983 | 0.89 | DPP8 (0.49) | DPP8DPP9KMT2AALDH1A1MAPT | |
| SCHEMBL6941021 | 0.88 | DPP8 (0.44) | DPP8DPP9KMT2AALDH1A1MAPT | |
| SCHEMBL6941351 | 0.87 | DPP8 (0.44) | DPP8DPP9KMT2AALDH1A1MAPT | |
| SCHEMBL6942902 | 0.85 | DPP8 (0.39) | DPP8DPP9KMT2ARECQLPREP | |
| SCHEMBL6946787 | 0.85 | DPP8 (0.42) | DPP8DPP9KMT2ARECQLPREP | |
| SCHEMBL6945227 | 0.85 | DPP8 (0.51) | DPP8DPP9ALDH1A1MAPTPREP | |
| SCHEMBL6945021 | 0.84 | DPP8 (0.40) | DPP8DPP9ALDH1A1MAPTKDM4E | |
| SCHEMBL9728223 | 0.82 | DPP8 (0.46) | DPP8DPP9 | |
| SCHEMBL8438227 | 0.81 | DPP8 (0.42) | DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL9040433 | 0.81 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |