Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944946 | 0.86 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL6944612 | 0.86 | ADAM17 (0.38) | — | |
| SCHEMBL6942423 | 0.86 | TGFBR1 (0.33) | TGFBR1P2RX3 | |
| SCHEMBL6945779 | 0.85 | TGFBR1 (0.33) | TGFBR1P2RX3 | |
| SCHEMBL6946755 | 0.83 | TGFBR1 (0.32) | TGFBR1P2RX3 | |
| SCHEMBL8097973 | 0.83 | P2RX3 (0.32) | TGFBR1P2RX3 | |
| SCHEMBL7938335 | 0.82 | TGFBR1 (0.33) | TGFBR1P2RX3 | |
| SCHEMBL6948116 | 0.79 | TGFBR1 (0.32) | TGFBR1P2RX3 | |
| SCHEMBL6947105 | 0.78 | P2RX3 (0.34) | TGFBR1P2RX3 | |
| SCHEMBL6943948 | 0.77 | TGFBR1 (0.33) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |