Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943244 | 0.86 | TGFBR1 (0.35) | — | |
| SCHEMBL6943076 | 0.82 | ADAM17 (0.39) | ADAM17 | |
| SCHEMBL6942646 | 0.82 | ADAM17 (0.40) | ADAM17CTSC | |
| SCHEMBL6939564 | 0.81 | ADAM17 (0.40) | ADAM17CTSC | |
| SCHEMBL8111670 | 0.79 | ADAM17 (0.38) | ADAM17CTSC | |
| SCHEMBL6940773 | 0.79 | ADAM17 (0.40) | ADAM17CTSC | |
| SCHEMBL6944954 | 0.78 | ADAM17 (0.37) | ADAM17CTSC | |
| SCHEMBL6984201 | 0.78 | ADAM17 (0.37) | ADAM17CTSC | |
| SCHEMBL6942591 | 0.76 | ADAM17 (0.38) | ADAM17CTSC | |
| SCHEMBL6942160 | 0.74 | ADAM17 (0.37) | ADAM17CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |