Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119637 | 0.99 | DPP8 (0.45) | DPP8DPP9MCHR1NPBWR1 | |
| SCHEMBL9120984 | 0.91 | OPRK1 (0.39) | DPP8DPP9MCHR1NPBWR1TDP1 | |
| SCHEMBL9040433 | 0.91 | ALDH1A1 (0.41) | MCHR1NPBWR1TDP1 | |
| SCHEMBL9040592 | 0.91 | ALDH1A1 (0.41) | MCHR1NPBWR1TDP1 | |
| SCHEMBL9199817 | 0.90 | TDP1 (0.40) | DPP8DPP9TDP1 | |
| SCHEMBL9120876 | 0.90 | ALDH1A1 (0.44) | DPP8DPP9 | |
| SCHEMBL8434820 | 0.89 | TDP1 (0.43) | DPP8DPP9TDP1 | |
| SCHEMBL8536750 | 0.88 | KCNJ1 (0.42) | — | |
| SCHEMBL8438589 | 0.88 | KCNJ1 (0.42) | — | |
| Dimethylamine SCHEMBL6943989 | 0.88 | ALDH1A1 (0.41) | DPP8DPP9MCHR1NPBWR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |