Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6943983 | 0.86 | DPP8 (0.49) | DPP8DPP9TGM2PREPTPSAB1 | |
| SCHEMBL6941021 | 0.86 | DPP8 (0.44) | DPP8DPP9PREPALDH1A1MAPT | |
| SCHEMBL6944285 | 0.85 | DPP8 (0.45) | DPP8DPP9P2RX7TGM2PREP | |
| SCHEMBL6941351 | 0.85 | DPP8 (0.44) | DPP8DPP9TGM2PREPALDH1A1 | |
| SCHEMBL6943475 | 0.85 | DPP8 (0.44) | DPP8DPP9PREPALDH1A1MAPT | |
| SCHEMBL6946646 | 0.83 | DPP8 (0.45) | DPP8DPP9NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL6946787 | 0.83 | DPP8 (0.42) | DPP8DPP9PREPTPSAB1TPSD1 | |
| SCHEMBL9728223 | 0.82 | DPP8 (0.46) | DPP8DPP9NPBWR1MCHR1TDP1 | |
| SCHEMBL8440385 | 0.82 | DPP8 (0.37) | DPP8DPP9ALDH1A1MAPTTDP1 | |
| SCHEMBL9040592 | 0.82 | ALDH1A1 (0.41) | NPBWR1MCHR1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641795-B9 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2003-01-29 | — | — | EP | disclosed |
| EP-0641795-B1 | CARBAPENEM DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5559224-A | Carbepenem derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0641795-A1 | CARBAPENEM DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |