SCHEMBL6943839

SCHEMBL6943839

COCCCOc1cc(CCCCCCC(C(=O)N[C@H](C(=O)NN2CCOCC2)C(C)C)(C(C)C)C(C)C)ccc1OC

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
REN P00797 16/20 0.44
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6940853 0.99 REN (0.45) RENKMT2AMEN1
SCHEMBL6943818 0.86 REN (0.43) RENKMT2AMEN1HTT
Hydrochloric Acid SCHEMBL6947174 0.86 REN (0.44) RENKMT2AMEN1HTT
SCHEMBL6943885 0.84 REN (0.44) RENKMT2AMEN1
SCHEMBL6943202 0.82 REN (0.55) REN
Hydrochloric Acid SCHEMBL6942968 0.81 REN (0.56) REN
Hydrochloric Acid SCHEMBL6947328 0.81 REN (0.57) REN
SCHEMBL6943317 0.81 REN (0.56) RENKMT2AMEN1HTT
SCHEMBL6940726 0.80 REN (0.52) RENKMT2AMEN1HTT
Hydrochloric Acid SCHEMBL6938981 0.80 REN (0.53) RENKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003103653-A1 METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO claimed