Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942710 | 0.87 | ADAM17 (0.46) | ADAM17MMP1MMP3MMP9MMP2 | |
| SCHEMBL6947136 | 0.83 | ADAM17 (0.44) | ADAM17MMP1MMP9MMP2GAA | |
| SCHEMBL6942460 | 0.83 | ADAM17 (0.46) | ADAM17MMP1MMP3MMP2MMP7 | |
| SCHEMBL6944742 | 0.82 | CHRNB2 (0.43) | ADAM17MMP1MMP3MMP2MMP7 | |
| SCHEMBL6984686 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A | |
| SCHEMBL6220502 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A | |
| SCHEMBL6220496 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A | |
| SCHEMBL6220497 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A | |
| SCHEMBL6220493 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A | |
| SCHEMBL6986484 | 0.81 | ADAM17 (0.48) | ADAM17POLBMAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |