Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948258 | 0.80 | PPARA (0.38) | RENMRGPRX4PPARAPPARGMAPT | |
| SCHEMBL6942587 | 0.75 | MRGPRX4 (0.44) | RENMRGPRX4FFAR4RXRA | |
| SCHEMBL6948450 | 0.73 | RAF1 (0.49) | MRGPRX4MAPTRXFP1FFAR4RXRA | |
| SCHEMBL6948152 | 0.73 | PPARA (0.43) | RENMRGPRX4PPARAPPARG | |
| SCHEMBL6948146 | 0.73 | PPARA (0.43) | RENMRGPRX4PPARAPPARG | |
| Methane SCHEMBL6947967 | 0.72 | RXFP1 (0.40) | PPARAPPARGMAPTRXFP1RXRA | |
| SCHEMBL6949592 | 0.72 | RXFP1 (0.50) | PPARAMAPTRXFP1POLBTDP1 | |
| SCHEMBL6044812 | 0.71 | REN (0.61) | REN | |
| SCHEMBL6044804 | 0.71 | REN (0.61) | REN | |
| SCHEMBL27773869 | 0.70 | PPARA (0.50) | PPARAPPARGMAPTRXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |