Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 3/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942587 | 0.84 | MRGPRX4 (0.44) | MRGPRX4RXRARXRBRXRGKDM4E | |
| SCHEMBL6944389 | 0.73 | REN (0.38) | MRGPRX4MAPTRXFP1MEN1KMT2A | |
| SCHEMBL9237645 | 0.72 | SMN1; SMN2 (0.64) | HDAC1HDAC2MAPTRXFP1ALDH1A1 | |
| SCHEMBL2960008 | 0.72 | SMN1; SMN2 (0.64) | HDAC1HDAC2MAPTRXFP1ALDH1A1 | |
| SCHEMBL6948258 | 0.72 | PPARA (0.38) | MRGPRX4MAPTRXFP1MEN1KMT2A | |
| Methane SCHEMBL6947967 | 0.72 | RXFP1 (0.40) | MAPTRXFP1RXRAALDH1A1 | |
| SCHEMBL6949592 | 0.72 | RXFP1 (0.50) | MAPTRXFP1ALDH1A1 | |
| SCHEMBL2302450 | 0.71 | SMN1; SMN2 (0.66) | HDAC1HDAC2MAPTRXFP1ALDH1A1 | |
| SCHEMBL7415347 | 0.69 | PPARA (0.58) | MAPTRXFP1 | |
| SCHEMBL9857811 | 0.68 | SMN1; SMN2 (0.51) | MAPTRXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |