Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949592 | 0.75 | RXFP1 (0.50) | RXFP1MAPTPPARACYP1A2ALDH1A1 | |
| SCHEMBL6942587 | 0.74 | MRGPRX4 (0.44) | ALDH1A1RXRATBXAS1 | |
| SCHEMBL6944389 | 0.72 | REN (0.38) | RXFP1MAPTPPARAPPARGRXRA | |
| SCHEMBL6948450 | 0.72 | RAF1 (0.49) | RXFP1MAPTALDH1A1RXRA | |
| SCHEMBL6948258 | 0.71 | PPARA (0.38) | RXFP1MAPTPPARAPPARGALDH1A1 | |
| SCHEMBL10935708 | 0.71 | MAPT (0.47) | RXFP1MAPTCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7415347 | 0.69 | PPARA (0.58) | RXFP1MAPTPPARAPPARGALOX5 | |
| SCHEMBL11725011 | 0.68 | GAA (0.55) | RXFP1MAPTCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL7095615 | 0.68 | PPARA (0.59) | PPARAPPARGALOX5POLBSELP | |
| SCHEMBL28432360 | 0.68 | GAA (0.55) | RXFP1MAPTCYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |