Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6706780 | 0.78 | PANK3 (0.49) | MAPTMAPK1SMN1; SMN2LMNAPANK3 | |
| SCHEMBL7258378 | 0.76 | MAPT (0.54) | MAPTMAPK1TSHRSMN1; SMN2ABCB1 | |
| SCHEMBL7256859 | 0.75 | MAPT (0.47) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6698918 | 0.74 | MAPT (0.53) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7253740 | 0.73 | MT-CO2 (0.55) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7253800 | 0.72 | ALDH1A1 (0.45) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL7253746 | 0.72 | ALDH1A1 (0.45) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL12157622 | 0.72 | NPY2R (0.49) | MAPTMAPK1SMN1; SMN2LMNANPC1 | |
| SCHEMBL7253240 | 0.71 | NR4A1 (0.44) | MAPTMAPK1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6648002 | 0.69 | MAPT (0.55) | MAPTMAPK1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289971-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 AND MTP INHIBITORS | GLAXO GROUP LIMITED (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001092241-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS APOB-100 AND MTP INHIBITORS | GLAXO GROUP LIMITED (GB) | 2001-12-06 | — | — | WO | disclosed |