Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256859 | 0.84 | MAPT (0.47) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL7258378 | 0.83 | MAPT (0.54) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL7253740 | 0.82 | MT-CO2 (0.55) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL7253746 | 0.81 | ALDH1A1 (0.45) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL7253800 | 0.81 | ALDH1A1 (0.45) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL7253222 | 0.75 | MAPT (0.51) | ESR2MAPTTSHRMAPK1ALDH1A1 | |
| SCHEMBL6702911 | 0.74 | L3MBTL1 (0.48) | LMNACREBBPRAB9AMT-CO2 | |
| SCHEMBL6698288 | 0.74 | L3MBTL1 (0.60) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7256854 | 0.72 | MAPKAPK2 (0.42) | NR4A1ESR2MAPTTSHRMAPK1 | |
| SCHEMBL6699799 | 0.71 | L3MBTL1 (0.49) | RAB9AMT-CO2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |