Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256859 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2MAPK1TSHRHSD17B10 | |
| SCHEMBL7253240 | 0.83 | NR4A1 (0.44) | MAPTSMN1; SMN2MAPK1TSHRPOLB | |
| SCHEMBL7253800 | 0.83 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MAPK1TSHRNR3C1 | |
| SCHEMBL7253740 | 0.83 | MT-CO2 (0.55) | MAPTSMN1; SMN2MAPK1TSHRPOLB | |
| SCHEMBL7253746 | 0.81 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MAPK1TSHRPOLB | |
| SCHEMBL6944856 | 0.76 | MAPT (0.47) | MAPTSMN1; SMN2MAPK1ABCB1CYP3A4 | |
| SCHEMBL7253222 | 0.76 | MAPT (0.51) | MAPTSMN1; SMN2MAPK1TSHRNAMPT | |
| SCHEMBL6702911 | 0.74 | L3MBTL1 (0.48) | RAB9A | |
| SCHEMBL7256854 | 0.73 | MAPKAPK2 (0.42) | MAPTMAPK1TSHRKDM4EHIF1A | |
| SCHEMBL6698288 | 0.73 | L3MBTL1 (0.60) | MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |