Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 6/20 | 0.33 |
| ▸ | HRH1 | P35367 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21367100 | 0.77 | GNAI3 (0.45) | USP2HRH2HRH1HRH3MAPK1 | |
| SCHEMBL27269583 | 0.76 | — | — | |
| SCHEMBL10924619 | 0.76 | ALDH1A1 (0.39) | KDM4EHRH3MAPK1ALDH1A1SLC29A1 | |
| SCHEMBL11575418 | 0.76 | — | — | |
| SCHEMBL12521983 | 0.75 | MAOB (0.44) | MEN1KMT2AHRH3KCNH2 | |
| SCHEMBL19865646 | 0.75 | CYP2D6 (0.35) | MEN1KMT2AUSP2KDM4EHRH3 | |
| SCHEMBL19865645 | 0.73 | GNAI3 (0.57) | KDM4EHRH3MAPK1KCNH2ALDH1A1 | |
| SCHEMBL6806038 | 0.73 | KDM4E (0.33) | HRH1KDM4EKCNH2ALDH1A1CYP1A2 | |
| SCHEMBL1108187 | 0.73 | MAPK1 (0.49) | MEN1KMT2AKDM4EHRH3MAPK1 | |
| SCHEMBL10930283 | 0.72 | HSD11B1 (0.42) | KDM4EHRH3MAPK1ALDH1A1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |