Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6148841 | 0.89 | ADAMTS4 (0.53) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL221435 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8837339 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL5145628 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL8837344 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL24734375 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL7264750 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL221434 | 0.86 | CTSL (0.71) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL6147101 | 0.85 | CTSL (0.57) | CTSLCTSBCTSSMEN1KMT2A | |
| SCHEMBL24740255 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2ALMNACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177168-A4 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA INC (US) | 2003-06-25 | — | — | EP | claimed |
| JP-2002541237-A | — | — | 2002-12-03 | — | — | JP | claimed |
| EP-1177168-A1 | CASPASE INHIBITORS AND THE USE THEREOF | Cytovia, Inc. (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000061542-A1 | CASPASE INHIBITORS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2000-10-19 | — | — | WO | claimed |