Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947807 | 0.74 | ALDH1A1 (0.47) | SLC6A2 | |
| SCHEMBL20674002 | 0.72 | KDM4E (0.47) | SLC6A2SLC6A4HTR4CACNA1GCACNA1H | |
| SCHEMBL2261817 | 0.72 | HTR4 (0.41) | SLC6A2SLC6A4HTR4CACNA1GCACNA1H | |
| SCHEMBL6948825 | 0.71 | MEN1 (0.46) | SLC6A2SLC6A4HTR4 | |
| SCHEMBL6644290 | 0.69 | MEN1 (0.41) | — | |
| SCHEMBL6951613 | 0.69 | PGR (0.46) | SLC6A2SLC6A4 | |
| SCHEMBL8565489 | 0.69 | MEN1 (0.44) | — | |
| SCHEMBL23937829 | 0.68 | DDB1 (0.56) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11033286 | 0.67 | HTR4 (0.45) | HTR4OPRL1 | |
| SCHEMBL30125366 | 0.65 | P2RX4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105388-B1 | N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES, PRODUCTION AND USE THEREOF | BASF AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-6458821-B1 | THE NOVEL SUBSTANCES ARE SUITABLE FOR CONTROLLING DISEASES. INTERESTING PROPERTIES AS POTENTIAL NEUROLEPTICS AND ANTIDEPRESSANTS | ABBOTT LABORATORIES | 2002-10-01 | — | — | US | disclosed |