Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948905 | 0.78 | HSPB1 (0.37) | PIN1HSPB1MAPTATMTDP1 | |
| SCHEMBL27581359 | 0.73 | PIN1 (0.39) | PIN1HTTMAPTATMTDP1 | |
| SCHEMBL6949963 | 0.73 | ALDH1A1 (0.43) | PIN1HTTHSPB1MAPTTDP1 | |
| SCHEMBL6949952 | 0.72 | PIN1 (0.42) | PIN1HSPB1MAPTATMTDP1 | |
| SCHEMBL193774 | 0.71 | ALDH1A1 (0.47) | HTTMAPTATMTDP1HPGD | |
| SCHEMBL30127220 | 0.71 | ALDH1A1 (0.47) | HTTMAPTATMTDP1HPGD | |
| SCHEMBL25983831 | 0.71 | CYP11B2 (0.37) | PIN1MAPTATMTDP1ALDH1A1 | |
| SCHEMBL21612777 | 0.70 | TDP1 (0.36) | PIN1HTTHSPB1MAPTATM | |
| SCHEMBL9632914 | 0.69 | MERTK (0.49) | HTTHSPB1MAPTTDP1HPGD | |
| SCHEMBL10812032 | 0.69 | MEN1 (0.44) | HTTHSPB1MAPTATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144380-A4 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1144380-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000032573-A1 | A META-NITRO PHENOL DERIVATIVE AND A PROCESS FOR PRODUCING IT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-06-08 | — | — | WO | disclosed |