Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946176 | 0.89 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL6942383 | 0.86 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL6946850 | 0.86 | TGFBR1 (0.31) | TGFBR1 | |
| SCHEMBL6943304 | 0.86 | TGFBR1 (0.34) | TGFBR1 | |
| SCHEMBL6942438 | 0.85 | HPGD (0.35) | TGFBR1 | |
| SCHEMBL6943580 | 0.85 | HPGD (0.32) | TGFBR1 | |
| SCHEMBL7131174 | 0.85 | ALDH1A1 (0.32) | TGFBR1 | |
| SCHEMBL6938018 | 0.84 | CCR3 (0.33) | — | |
| SCHEMBL6945332 | 0.83 | HPGD (0.34) | TGFBR1 | |
| SCHEMBL6943242 | 0.83 | L3MBTL1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |