Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938018 | 0.91 | CCR3 (0.33) | ALDH1A1MAPT | |
| SCHEMBL6945332 | 0.90 | HPGD (0.34) | HPGDALDH1A1MAPTTGFBR1SMN1; SMN2 | |
| SCHEMBL6943242 | 0.88 | L3MBTL1 (0.32) | HPGDALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6946921 | 0.88 | — | — | |
| SCHEMBL6946176 | 0.86 | TGFBR1 (0.33) | P2RX3TGFBR1 | |
| SCHEMBL6946104 | 0.85 | TGFBR1 (0.31) | TGFBR1 | |
| SCHEMBL7131174 | 0.84 | ALDH1A1 (0.32) | HPGDALDH1A1TGFBR1 | |
| SCHEMBL6940050 | 0.84 | CTSB (0.32) | P2RX3TGFBR1L3MBTL1 | |
| SCHEMBL6940042 | 0.84 | SMN1; SMN2 (0.33) | HPGDALDH1A1MAPTSMN1; SMN2ATM | |
| SCHEMBL6940210 | 0.84 | ALDH1A1 (0.34) | ALOX12NPSR1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |