Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993660 | 0.75 | TP53 (0.39) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL13713493 | 0.74 | OPRM1 (0.43) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL852406 | 0.74 | PAX8 (0.42) | RAB9ATSHRGRM5CYP3A4CYP1A2 | |
| SCHEMBL8761336 | 0.73 | CHRNB2 (0.61) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL17882440 | 0.72 | LMNA (0.43) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| Dibutyl Phthalate SCHEMBL8167118 | 0.72 | TSHR (0.76) | SMN1; SMN2LMNATP53HSD17B10TSHR | |
| SCHEMBL15174120 | 0.72 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL20909909 | 0.72 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1MAPTTP53 | |
| SCHEMBL11037713 | 0.71 | NCEH1 (0.47) | RAB9ALMNAMAPTHSD17B10L3MBTL1 | |
| SCHEMBL19477824 | 0.71 | TSHR (0.41) | SMN1; SMN2RAB9ALMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946180-A4 | METHOD FOR STIMULATING BONE FORMATION | SMITHKLINE BEECHAM CORP (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0946180-A1 | METHOD FOR STIMULATING BONE FORMATION | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998015278-A1 | METHOD FOR STIMULATING BONE FORMATION | SMITHKLINE BEECHAM CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |