Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112167 | 0.72 | CA1 (0.47) | HIF1ASLC7A5CA1CA2L3MBTL1 | |
| SCHEMBL17949865 | 0.72 | HIF1A (0.42) | HIF1ASLC7A5CA1CA2L3MBTL1 | |
| SCHEMBL8111820 | 0.71 | MMP1 (0.31) | MMP1MMP2MMP8MMP13 | |
| SCHEMBL4677717 | 0.70 | SLC7A5 (0.56) | LARS1HIF1ASLC7A5ANPEPDNPEP | |
| Hydrochloric Acid SCHEMBL27471876 | 0.70 | CA1 (0.45) | MMP2MMP8HIF1ASLC7A5CA1 | |
| SCHEMBL19559844 | 0.70 | SLC7A5 (0.56) | LARS1HIF1ASLC7A5ANPEPDNPEP | |
| SCHEMBL8330499 | 0.70 | SLC7A5 (0.56) | LARS1HIF1ASLC7A5ANPEPDNPEP | |
| SCHEMBL8097957 | 0.69 | GAA (0.57) | LARS1 | |
| SCHEMBL27470984 | 0.68 | SLC1A3 (0.39) | MMP1MMP2MMP8MMP13HIF1A | |
| Bromide SCHEMBL11107160 | 0.68 | SLC7A5 (0.54) | LARS1HIF1ASLC7A5ANPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |