Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325545 | 0.78 | CYP11B1 (0.50) | AOC3NPC1RAB9AMEN1CASP3 | |
| SCHEMBL27928712 | 0.73 | MAOA (0.43) | AOC3NPC1RAB9ACYP2A6BRD4 | |
| SCHEMBL8087823 | 0.72 | HRH3 (0.50) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL17861255 | 0.71 | AHR (0.43) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL2940750 | 0.71 | HRH3 (0.49) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL856331 | 0.71 | DAO (0.46) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL29684111 | 0.71 | HRH3 (0.49) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL7194941 | 0.70 | RAB9A (0.47) | AOC3NPC1RAB9AKDM4EMAPT | |
| SCHEMBL92726 | 0.69 | HRH3 (0.53) | AOC3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL38661680 | 0.69 | HRH3 (0.53) | AOC3KDM4EHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619391-B | Heterocyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2022-08-05 | — | — | CN | claimed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | claimed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | claimed |
| CN-112533930-B | Organometallic complexes, polymers, mixtures, compositions, and organic electronic devices comprising the same | 广州华睿光电材料有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-112533930-A | Organometallic complexes, polymers containing the same, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-1275646-A4 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEM RES (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001074807-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2001-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | AIFM1, BAX, CASP3 | AOC3 4147/4885NPC1 1080/4885RAB9A 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.