Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313888 | 0.83 | CYP19A1 (0.42) | TSHRCYP3A4TDP1MAPK1ATM | |
| SCHEMBL2772403 | 0.83 | ALDH5A1 (0.59) | TSHRMAPTNPSR1MAPK1ALDH5A1 | |
| SCHEMBL14893975 | 0.83 | TDP1 (0.56) | TSHRCYP3A4CASP6MAPTTDP1 | |
| SCHEMBL3903310 | 0.83 | ALDH1A1 (0.45) | CYP3A4MAPTNPSR1MAPK1ALDH5A1 | |
| SCHEMBL1983738 | 0.83 | VCAM1 (0.59) | TDP1VCAM1POLBALDH1A1 | |
| SCHEMBL9158 | 0.83 | ALDH1A1 (0.55) | MAPTNPSR1TDP1ATMVCAM1 | |
| SCHEMBL5716648 | 0.83 | MAPT (0.50) | TSHRCYP3A4MAPTTDP1POLB | |
| SCHEMBL1225410 | 0.83 | ALDH1A1 (0.53) | TSHRCYP3A4MAPTNPSR1MAPK1 | |
| SCHEMBL4602487 | 0.80 | PTGS2 (0.36) | CYP3A4MAPTNPSR1TDP1MAPK1 | |
| SCHEMBL18138457 | 0.79 | TSHR (0.52) | TSHRCYP3A4CASP6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230223-B1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA SA (FR) | 2004-02-25 | — | — | EP | disclosed |
| EP-1230223-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | Aventis Pharma S.A. (FR) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032630-A1 | OLIGOBENZIMIDAZOLE DERIVATIVES AND THEIR USE AS DNA TRANSFECTION AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-05-10 | — | — | WO | disclosed |