Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4109091 | 0.81 | HASPIN (0.37) | KMT2AHASPINALOX15ADORA3ALDH1A1 | |
| SCHEMBL4987746 | 0.79 | KMT2A (0.40) | KMT2AHASPINPOLBCYP1A2ALOX15 | |
| SCHEMBL7048936 | 0.74 | MAPT (0.40) | KMT2APOLBCYP1A2ALOX15ADORA3 | |
| SCHEMBL5045978 | 0.71 | GPR84 (0.50) | KMT2AHASPINALDH1A1HTTMEN1 | |
| SCHEMBL8752016 | 0.65 | NPSR1 (0.36) | KMT2APOLBALOX15ALDH1A1 | |
| SCHEMBL6135340 | 0.62 | HPGD (0.40) | KMT2AHASPINALOX15ADORA3ALDH1A1 | |
| SCHEMBL1879639 | 0.62 | KMT2A (0.40) | KMT2APOLBALOX15ALDH1A1HTT | |
| SCHEMBL22809469 | 0.62 | HPGD (0.46) | KMT2APOLBADORA3MEN1ADORA2A | |
| SCHEMBL61731 | 0.61 | SMN1; SMN2 (0.43) | KMT2ASMYD3ALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL482012 | 0.61 | SMN1; SMN2 (0.43) | KMT2ASMYD3ALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996446-B1 | NOVEL SUBSTITUTED IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-09-17 | — | — | EP | disclosed |