Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762871 | 0.75 | NAMPT (0.40) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL6948393 | 0.73 | MAPT (0.46) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL760652 | 0.71 | NAMPT (0.42) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL7371057 | 0.67 | BRD4 (0.44) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5189062 | 0.67 | NAMPT (0.41) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL5444456 | 0.67 | NAMPT (0.41) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL5236831 | 0.67 | L3MBTL1 (0.42) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL266599 | 0.65 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2314210 | 0.65 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL4899883 | 0.64 | BRD4 (0.47) | ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | claimed |