Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRS3 | P32247 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950048 | 0.86 | RNASEH1 (0.50) | DHODHRAB9ANPC1BRS3HDAC6 | |
| SCHEMBL6945584 | 0.85 | ALOX15 (0.48) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL8687823 | 0.82 | HDAC6 (0.43) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6951783 | 0.81 | DHODH (0.47) | DHODHRAB9ANPC1BRS3HDAC6 | |
| SCHEMBL6947548 | 0.81 | MAPT (0.43) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6948954 | 0.81 | NPC1 (0.55) | DHODHRAB9ANPC1BRS3HDAC6 | |
| SCHEMBL6948941 | 0.80 | TUBB4A (0.53) | DHODHTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6945348 | 0.76 | DHODH (0.42) | DHODHRAB9ANPC1BRS3HDAC6 | |
| SCHEMBL10212734 | 0.74 | DHODH (1.00) | DHODH | |
| SCHEMBL29412049 | 0.74 | PARP1 (0.60) | DHODHRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |