Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NMT1 | P30419 | 4/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942891 | 0.91 | MAPT (0.47) | MEN1HSP90AA1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6948278 | 0.89 | PRMT5 (0.45) | MEN1HSP90AA1KMT2AHPGDGABRA1 | |
| SCHEMBL6952578 | 0.88 | DHODH (0.52) | LTB4RLTB4R2FFAR1FFAR4DHODH | |
| SCHEMBL6948956 | 0.84 | DHODH (0.54) | MEN1HSP90AA1KMT2AHPGDGABRA1 | |
| SCHEMBL6949863 | 0.81 | SCN1A (0.42) | MEN1HSP90AA1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6945413 | 0.81 | LMNA (0.45) | KMT2AHPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL6949850 | 0.79 | MAPT (0.49) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL6953656 | 0.78 | MAPT (0.44) | MEN1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL6945589 | 0.76 | TUBB4A (0.46) | MEN1HSP90AA1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6945368 | 0.76 | RAB9A (0.52) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |