Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.41 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.41 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950532 | 0.90 | L3MBTL1 (0.41) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6948963 | 0.84 | ITGB3 (0.46) | LMNAHPGDHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6358943 | 0.81 | FOLH1 (0.48) | GPR132CMKLR2CMKLR1EPHX2FOLH1 | |
| SCHEMBL6954777 | 0.81 | FOLH1 (0.47) | GPR132CMKLR2CMKLR1EPHX2FOLH1 | |
| SCHEMBL29538593 | 0.77 | GPR132 (0.50) | LMNAHPGDHTTSMN1; SMN2GPR132 | |
| SCHEMBL7832742 | 0.74 | GPR132 (0.45) | GPR132CMKLR2CMKLR1ALDH1A1FOLH1 | |
| SCHEMBL6776672 | 0.74 | GPR132 (0.52) | GPR132CMKLR2CMKLR1FOLH1 | |
| SCHEMBL6778695 | 0.74 | GPR132 (0.43) | LMNAHPGDHTTSMN1; SMN2GPR132 | |
| SCHEMBL31016499 | 0.74 | OPRD1 (0.45) | LMNAHPGDHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6778944 | 0.73 | GPR132 (0.44) | GPR132CMKLR2CMKLR1FOLH1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | claimed |
| EP-0804418-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-03-26 | — | — | EP | disclosed |
| US-5639765-A | OSTEOPOROSIS, PAGET*S DISEASE | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |