Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128776 | 0.82 | CA12 (0.53) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL6950385 | 0.79 | LMNA (0.53) | ALDH1A1TSHRJMJD6MAPTKDM4E | |
| SCHEMBL6953148 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRJMJD6PLA2G1BATG4B | |
| SCHEMBL6952030 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRPLA2G1BATG4BNPC1 | |
| SCHEMBL6948241 | 0.77 | ESR1 (0.54) | TSHRNPC1RAB9AMAPT | |
| SCHEMBL109308 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRJMJD6PLA2G1BATG4B | |
| SCHEMBL6954003 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TSHRJMJD6PLA2G1BATG4B | |
| SCHEMBL6950001 | 0.76 | CA12 (0.53) | ALDH1A1JMJD6NPC1RAB9AHTT | |
| SCHEMBL6580266 | 0.75 | ALDH1A1 (0.59) | ALDH1A1TSHRJMJD6PLA2G1BATG4B | |
| SCHEMBL110051 | 0.75 | ALDH1A1 (0.64) | ALDH1A1TSHRPLA2G1BATG4BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |