Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950103 | 0.81 | ALDH1A1 (0.38) | MAPTPSMB5 | |
| Malonic Acid Diethyl Ester SCHEMBL8506948 | 0.76 | ALDH1A1 (0.35) | MAPTPSMB5 | |
| SCHEMBL9978729 | 0.76 | CYP3A4 (0.46) | MAPT | |
| SCHEMBL2673397 | 0.75 | MAPT (0.46) | MAPT | |
| SCHEMBL7387704 | 0.71 | CTNNB1 (0.55) | MAPT | |
| SCHEMBL2672622 | 0.70 | PPARG (0.47) | MAPT | |
| SCHEMBL6956656 | 0.69 | CYP4F2 (0.46) | MAPT | |
| SCHEMBL11268815 | 0.68 | ALDH1A1 (0.45) | MAPT | |
| SCHEMBL2386216 | 0.68 | MAPT (0.46) | MAPT | |
| SCHEMBL4330321 | 0.68 | MAPT (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |