SCHEMBL695012

SCHEMBL695012

COC(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.83
RAB9A P51151 5/20 0.63
MAPT P10636 3/20 0.63
L3MBTL1 Q9Y468 3/20 0.63
CASP3 P42574 1/20 0.63
SENP8 Q96LD8 1/20 0.63
SENP7 Q9BQF6 1/20 0.63
SENP6 Q9GZR1 1/20 0.63
ALDH1A1 P00352 3/20 0.61
CA1 P00915 5/20 0.59
CA2 P00918 5/20 0.59
CA12 O43570 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
CA7 P43166 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
NPC1 O15118 3/20 0.59
PTPN1 P18031 1/20 0.59
HPGD P15428 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL27524744 0.98 TSHR (0.86) TSHRRAB9AMAPTL3MBTL1CASP3
SCHEMBL13019477 0.94 TSHR (0.73) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL28249321 0.93 TSHR (0.95) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL28140701 0.92 TSHR (0.70) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL29831725 0.91 TSHR (1.00) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL1867855 0.91 TSHR (1.00) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL29039896 0.91 TSHR (1.00) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL1332323 0.91 TSHR (1.00) TSHRRAB9AMAPTL3MBTL1CASP3
Methyl Benzoate SCHEMBL28945661 0.91 TSHR (1.00) TSHRRAB9AMAPTL3MBTL1CASP3
SCHEMBL2337244 0.91 CA1 (0.70) TSHRRAB9AMAPTL3MBTL1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US claimed
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS UNIV CORNELL (US) 2026-03-26 US disclosed
US-20260027035-A1 PHOTOPOLYMERIZATION INITIATOR KJ CHEMICALS CORPORATION (JP) 2026-01-29 US disclosed
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
EP-4606824-A1 PHOTOPOLYMERIZATION INITIATOR KJ Chemicals Corporation (JP) 2025-08-27 EP disclosed
CN-120019084-A Photopolymerization initiator 科巨希化学股份有限公司 2025-05-16 CN disclosed
EP-3936192-B1 PYRROLOPYRAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2025-04-09 EP disclosed
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-03-13 US disclosed
US-12240855-B2 Pyrrolopyrazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-03-04 US disclosed
EP-3981754-B1 METHOD FOR MANUFACTURING 1-HALO-2-FLUOROETHYLENE DAIKIN IND LTD (JP) 2024-11-06 EP disclosed
US-4498963-A Photopolymerizable composition containing perester photoinitiator and photopolymerization process BOWLING GREEN STATE UNIVERSITY (US) 1985-02-12 US disclosed
US-4499299-A Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1985-02-12 US disclosed
US-4416826-A PHOTOINITIATORS FOR POLYMERIZATION OF ETHYLENICALLY UNSATURATED MATERIALS BOWLING GREEN STATE UNIVERSITY, AN EDUCATIONAL INSTITUTION OF OH. 1983-11-22 US disclosed
EP-0083228-A1 Pharmaceutically active phenylcarboxylic acid derivatives ICI AMERICAS INC. (US) 1983-07-06 EP disclosed
US-4347383-A BY REACTING BENZOPHENONE-IMINE WITH OXYGEN OR BENZOPHENONE WITH OXYGEN AND AMMONIA MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-08-31 US disclosed
EP-0000705-B1 USE OF ESTERS OR AMIDES OF BENZOYLBENZOIC ACIDS AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE COMPOSITION CONTAINING THEM STAUFFER CHEMICAL COMPANY (US) 1981-02-11 EP disclosed
EP-0000705-A1 Use of esters or amides of benzoylbenzoic acids as photoinitiators and photopolymerisable composition containing them STAUFFER CHEMICAL COMPANY (US) 1979-02-21 EP disclosed
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US disclosed
US-4067791-A BIS/DIETHYLAMINO/BENZOPHENONE AND BENZOYLBENZOIC ACID ESTER AS PHO OINITIATORS TOYO INK MANUFACTURING CO., LTD. (JA) 1978-01-10 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084056-A1 SUBSTITUTED OXOISOINDOLINYL PIPERIDINE-2,6-DIONE COMPOUNDS CCNA1, CCNI, CCNE1 TSHR 2650/4885RAB9A 2541/4885MAPT 2100/4885
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS ME3, ME2, SLC25A11 TSHR 4145/4885RAB9A 3129/4885MAPT 1856/4885
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C5, C1S, C9 TSHR 3056/4885RAB9A 1268/4885MAPT 1464/4885
US-12240855-B2 Pyrrolopyrazole derivative PTDSS1, PTDSS2, SMPD1 TSHR 4443/4885RAB9A 685/4885MAPT 4781/4885
US-20260027035-A1 PHOTOPOLYMERIZATION INITIATOR TRPA1, MTR, MGMT TSHR 1914/4885RAB9A 4780/4885MAPT 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.