Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.55 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169133 | 0.98 | HTR4 (0.54) | HTR3AHTR4F10DRD4MEN1 | |
| SCHEMBL8173531 | 0.98 | HTR3A (0.53) | HTR3AHTR4F10DRD4MEN1 | |
| SCHEMBL6952310 | 0.94 | HTR4 (0.55) | HTR3AHTR4F10DRD4MEN1 | |
| Hydrochloric Acid SCHEMBL6952254 | 0.93 | HTR4 (0.55) | HTR3AHTR4F10DRD4MEN1 | |
| SCHEMBL6947363 | 0.88 | HTR3A (0.56) | HTR3AHTR4F10MEN1ALDH1A1 | |
| SCHEMBL6956463 | 0.88 | HTR3A (0.59) | HTR3AHTR4F10MEN1ALDH1A1 | |
| SCHEMBL8172300 | 0.86 | HTR4 (0.57) | HTR3AHTR4F10MEN1ALDH1A1 | |
| SCHEMBL8173299 | 0.86 | HTR3A (0.54) | HTR3AHTR4F10MEN1ALDH1A1 | |
| SCHEMBL8162100 | 0.86 | HTR3A (0.57) | HTR3AHTR4F10MEN1ALDH1A1 | |
| SCHEMBL8173282 | 0.86 | HTR3A (0.57) | HTR3AHTR4F10MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |