Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.54 |
| ▸ | HTR3A | P46098 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950822 | 0.98 | HTR3A (0.55) | HTR4HTR3ADRD4POLBF10 | |
| SCHEMBL8173531 | 0.96 | HTR3A (0.53) | HTR4HTR3ADRD4F10MEN1 | |
| SCHEMBL6952310 | 0.96 | HTR4 (0.55) | HTR4HTR3ADRD4POLBF10 | |
| Hydrochloric Acid SCHEMBL6952254 | 0.95 | HTR4 (0.55) | HTR4HTR3ADRD4POLBF10 | |
| SCHEMBL8172300 | 0.89 | HTR4 (0.57) | HTR4HTR3AF10MEN1KMT2A | |
| SCHEMBL6947363 | 0.87 | HTR3A (0.56) | HTR4HTR3AF10MEN1KMT2A | |
| SCHEMBL8162100 | 0.86 | HTR3A (0.57) | HTR4HTR3AF10MEN1KMT2A | |
| SCHEMBL6956463 | 0.86 | HTR3A (0.59) | HTR4HTR3AF10MEN1KMT2A | |
| SCHEMBL6947999 | 0.85 | ACHE (0.64) | HTR4 | |
| SCHEMBL8173299 | 0.85 | HTR3A (0.54) | HTR4HTR3AF10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |