Water

Water

SCHEMBL6950940

O.O.[Ti].[V]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8027163 1.00
Water SCHEMBL19946487 0.87
Water SCHEMBL30377395 0.87
Water SCHEMBL31182206 0.87
Water SCHEMBL23298299 0.82
Water SCHEMBL168325 0.82
Water SCHEMBL22471762 0.82
Water SCHEMBL21358072 0.82
Water SCHEMBL10378772 0.82
Water SCHEMBL60837 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113912109-B Preparation method of nano titanium dioxide porous material 成都先进金属材料产业技术研究院股份有限公司 2023-04-25 CN claimed
CN-113912109-A Preparation method of nano titanium dioxide porous material 成都先进金属材料产业技术研究院股份有限公司 2022-01-11 CN claimed
US-20180239070-A1 MODIFYING OPTICAL PROPERTIES OF THIN FILM STRUCTURES USING AN ABSORBING ELEMENT PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-08-23 US claimed
CN-113912109-B Preparation method of nano titanium dioxide porous material 成都先进金属材料产业技术研究院股份有限公司 2023-04-25 CN disclosed
CN-113912109-A Preparation method of nano titanium dioxide porous material 成都先进金属材料产业技术研究院股份有限公司 2022-01-11 CN disclosed
US-20180239070-A1 MODIFYING OPTICAL PROPERTIES OF THIN FILM STRUCTURES USING AN ABSORBING ELEMENT PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-08-23 US disclosed
CN-105188924-A Selective catalytic reduction catalyst system BASF SE 2015-12-23 CN disclosed
CN-105026038-A Selective catalytic reduction catalyst system BASF SE 2015-11-04 CN disclosed
CN-102834594-B Exhaust gas purification system for internal combustion engine TOYOTA MOTOR CORP. (JP) 2014-10-22 CN disclosed
CN-102037230-B Abnormality diagnosis device and abnormality diagnosis method for NOx sensor TOYOTA MOTOR CORP 2014-01-22 CN disclosed
CN-101896701-B Apparatus for making diagnosis of abnormality of NOx catalyst and method for making diagnosis of abnormality TOYOTA MOTOR CORP 2013-01-09 CN disclosed
CN-101316992-B Exhaust gas purifier for internal combustion engine TOYOTA MOTOR CO LTD 2010-06-09 CN disclosed
CN-101668931-A Apparatus for diagnosis of abnormality in exhaust gas purification system TOYOTA MOTOR CO LTD 2010-03-10 CN disclosed
CN-101316992-A Exhaust gas purifier for internal combustion engine TOYOTA MOTOR CO LTD (JP) 2008-12-03 CN disclosed
CN-101305169-A Exhaust purifying system for internal combustion engine TOYOTA MOTOR CO LTD (JP) 2008-11-12 CN disclosed
CN-101292077-A Exhaust cleaner for internal combustion engine TOYOTA MOTOR CO LTD (JP) 2008-10-22 CN disclosed
CN-101171407-A Exhaust gas purification device for internal combustion engine TOYOTA MOTOR CO LTD (JP) 2008-04-30 CN disclosed
EP-0985648-B1 GAS-PHASE OXIDATION PROCESS AND PROCESS FOR THE PREPARATION OF PHTHALIC ANHYDRIDE NIPPON STEEL CHEMICAL CO (JP) 2003-05-21 EP disclosed
US-6369240-B1 VAPOR PHASE OXIDATION OF HYDROCARBONS USING OXYGEN AND A FIXED BED NIPPON STEEL CHEMICAL CO., LTD. (JP) 2002-04-09 US disclosed
EP-0985648-A1 GAS-PHASE OXIDIZATION PROCESS AND PROCESS FOR THE PREPARATION OF PHTHALIC ANHYDRIDE NIPPON STEEL CHEMICAL CO., LTD. (JP) 2000-03-15 EP disclosed