Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959865 | 0.94 | BCHE (0.49) | BCHEACHEADRA2AADRA2BADRA2C | |
| SCHEMBL6959528 | 0.93 | CCR3 (0.46) | HTR2ACCR3 | |
| SCHEMBL6955648 | 0.93 | HTR2A (0.48) | BCHEHTR2ACCR3 | |
| SCHEMBL7355747 | 0.92 | BCHE (0.41) | BCHEACHEHTR2ACCR3ADRA2A | |
| SCHEMBL7075871 | 0.91 | HTR1A (0.43) | HTR2ACCR3 | |
| SCHEMBL6959392 | 0.88 | ADRA2A (0.54) | HTR2AADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL7877114 | 0.88 | NPC1 (0.49) | BCHEACHEHTR2ACCR3ADRA2A | |
| SCHEMBL6949399 | 0.88 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6954023 | 0.87 | HTR1A (0.49) | HTR2ACCR3ADRA2AADRA2BADRA2C | |
| SCHEMBL6958383 | 0.87 | HTR1A (0.52) | BCHEACHEHTR2ACCR3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |