Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958383 | 0.94 | HTR1A (0.52) | HTR2ACCR3HTR1ASLC6A4BCHE | |
| SCHEMBL6951247 | 0.93 | BCHE (0.42) | HTR2ACCR3BCHE | |
| SCHEMBL6959528 | 0.92 | CCR3 (0.46) | HTR2ACCR3HTR1A | |
| SCHEMBL7075871 | 0.90 | HTR1A (0.43) | HTR2ACCR3HTR1A | |
| SCHEMBL6947219 | 0.89 | HTR1A (0.52) | HTR2ACCR3HTR1ASLC6A4 | |
| SCHEMBL7879009 | 0.88 | HTR1A (0.55) | HTR2ACCR3HTR1ASLC6A4CARM1 | |
| SCHEMBL6959392 | 0.87 | ADRA2A (0.54) | HTR2AHTR1ASLC6A4 | |
| SCHEMBL6949399 | 0.87 | ADRA2A (0.47) | HTR1ASLC6A4 | |
| SCHEMBL6959865 | 0.87 | BCHE (0.49) | HTR1ASLC6A4BCHE | |
| SCHEMBL7355747 | 0.86 | BCHE (0.41) | HTR2ACCR3HTR1ASLC6A4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |