Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 5/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11840647 | 0.90 | PLA2G4A (0.51) | PLA2G4ASCN9AMTNR1AMTNR1BABCB1 | |
| SCHEMBL4263937 | 0.86 | WNK1 (0.52) | PLA2G4ASCN9AMTNR1AMTNR1BABCB1 | |
| SCHEMBL8454150 | 0.86 | HTR7 (0.56) | PLA2G4ASCN9ANR4A2RORCHTR7 | |
| SCHEMBL5609615 | 0.85 | L3MBTL1 (0.54) | PLA2G4ASCN9AMTNR1AMTNR1BABCB1 | |
| SCHEMBL31398364 | 0.82 | SCN9A (0.69) | PLA2G4ASCN9AMTNR1AMTNR1BABCB1 | |
| SCHEMBL8174123 | 0.80 | PLA2G4A (0.52) | PLA2G4AMTNR1AMTNR1BABCB1HTR6 | |
| SCHEMBL10946754 | 0.80 | AKR1C3 (0.69) | PLA2G4AMTNR1AMTNR1BABCB1HTR6 | |
| SCHEMBL8174658 | 0.80 | HTR7 (0.58) | SCN9ARORCHTR7CDC25A | |
| SCHEMBL12918558 | 0.80 | NR4A2 (0.63) | PLA2G4ANR4A2RORCTP53MAPT | |
| SCHEMBL7692305 | 0.80 | CHRM1 (0.65) | MTNR1AMTNR1BHTR6CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |