Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957950 | 0.92 | LMNA (0.50) | LMNACNR1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL8890569 | 0.88 | KMT2A (0.55) | LMNACNR1RECQLKMT2AMEN1 | |
| SCHEMBL6962998 | 0.88 | NPC1 (0.47) | LMNACNR1RECQLKMT2AMEN1 | |
| SCHEMBL6964188 | 0.88 | MPO (0.51) | LMNACNR1RECQLKMT2AALDH1A1 | |
| SCHEMBL6950919 | 0.85 | LMNA (0.45) | LMNARECQLKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6961502 | 0.85 | NPC1 (0.58) | LMNACNR1RECQLKMT2AALDH1A1 | |
| SCHEMBL6963530 | 0.84 | HTT (0.44) | LMNAKMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6958370 | 0.82 | ALDH1A1 (0.48) | LMNACNR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6964701 | 0.82 | KMT2A (0.43) | LMNARECQLKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6963954 | 0.80 | HTT (0.42) | LMNAKMT2AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |