Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CCNK | O75909 | 1/20 | 0.45 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957950 | 0.90 | LMNA (0.50) | KMT2ALMNARECQLSMN1; SMN2RAB9A | |
| SCHEMBL6952292 | 0.88 | LMNA (0.53) | KMT2ALMNARECQLSMN1; SMN2RAB9A | |
| SCHEMBL6957933 | 0.86 | KMT2A (0.56) | KMT2ALMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL6950919 | 0.86 | LMNA (0.45) | KMT2ALMNARECQLSMN1; SMN2GAA | |
| SCHEMBL6963530 | 0.84 | HTT (0.44) | KMT2ALMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL6958370 | 0.84 | ALDH1A1 (0.48) | KMT2ALMNASMN1; SMN2KDM4ERAB9A | |
| SCHEMBL6963954 | 0.83 | HTT (0.42) | KMT2ALMNASMN1; SMN2KDM4EHPGD | |
| SCHEMBL6964701 | 0.82 | KMT2A (0.43) | KMT2ALMNARECQLSMN1; SMN2MEN1 | |
| SCHEMBL6962998 | 0.82 | NPC1 (0.47) | KMT2ALMNARECQLSMN1; SMN2RAB9A | |
| SCHEMBL6964188 | 0.82 | MPO (0.51) | KMT2ALMNARECQLSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |